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In the testis tight junctions between Sertoli cells are an important structural element of the BTB restricting the movement of water,solutes, and immune cells from the circulation to the adluminal compartment of the seminiferous tubule, which creates a unique microenvi-ronment for spermatogenesis.
Prasugrelversus clopidogrel in patients with acute coronary syn-dromes.
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In other chapters the reader will learnways to limit the need for traditional animal studies and theways that in vitro procedures can be performed more quicklyand economically than whole animal studies. Afraction of the drug molecules present in plasma areremoved on each passage through the organs ofelimination.
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